Cure For Baldness

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While there has been speculation about a connection between early-onset androgenetic alopecia and heart disease, a review of articles from 1954 to 1999 found no conclusive connection between baldness and coronary artery disease.

One theory, advanced by Muscarella and Cunningham, suggests baldness evolved in males through sexual selection as an enhanced signal of aging and social maturity, whereby aggression and risk-taking decrease and nurturing behaviors increase.

Beards and a full head of hair were seen as being more aggressive and less socially mature, and baldness was associated with more social maturity.

Research indicates that susceptibility to premature male pattern baldness is largely X-linked. Large studies in 2005 and 2007 stress the importance of the maternal line in the inheritance of male pattern baldness.

Research in 2007 suggests another gene on the X chromosome, that lies close to the androgen receptor gene, is an important gene in male pattern baldness. This gene is also involved in a type of baldness associated with mental retardation.

The amount and patterns of baldness can vary greatly; it ranges from male and female pattern alopecia (androgenic alopecia, also called androgenetic alopecia or alopecia androgenetic), alopecia areata, which involves the loss of some of the hair from the head, and alopecia totalis, which involves the loss of all head hair, to the most extreme form, alopecia universalis, which involves the loss of all hair from the head and the body.

A common myth about male-pattern baldness is that you inherit baldness through your mother’s male relatives. Actually, baldness can come from either side of the family, or both.

Many companies have built a successful business selling products that reverse baldness, by allegedly regrowing hair, transplanting hair or selling hairpieces. The general public has become accepting of the shaved head as well, but female baldness is less socially acceptable.

The trigger for this type of baldness (called androgenetic alopecia) is DHT, a powerful sex hormone, body, and facial hair growth promoter that can adversely affect the prostate as well as the hair located on the head.

Male pattern baldness is classified on the Hamilton-Norwood scale I-VII. It was previously believed that baldness was inherited from the maternal grandfather. Most likely, inheritance is technically “autosomal dominant with mixed penetrance.

More than half of men are affected by male pattern baldness by age 50, and baldness treatments are estimated to be a US $1 billion per year industry. Since the 1980s, drug therapy has increasingly become a realistic management option for baldness for men and women.

Increased understanding of the role of dihydrotestosterone (DHT) in male and female pattern baldness has led to targeted intervention to prevent this hormone from acting on receptors in the scalp.

Alopecia areata is an autoimmune disorder also known as “spot baldness” that can result in hair loss ranging from just one location (Alopecia areata monolocularis) to every hair on the entire body (Alopecia areata universalis).

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